The SETDB1 antibody from Wuhan Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to SET domain bifurcated histone lysine methyltransferase 1, and SETDB1. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The SETDB1 antibody has been validated for the following applications: EIA, Immunoassay, ELISA, Immunohistochemistry, and Western Blot.
Description
This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described